Dry Granulation and Roller Compaction Technology
Dry Granulation and Roller Compaction Technology. The live broadcast was attended by nearly 250 individuals from around the world.
The program focused on the basic mechanical principles used for granulation and compaction of pharmaceuticals and chemicals. Compaction refers to the compression of powders into a solid form called “flakes”. Compressing the powder into flakes increases the bulk density of the material for the final product. With roller compaction technology a second step is often used to granulize the compressed product to improve the flowability, decrease the volume needed to store, package or distribute and alter how a particle reacts when used. Granulation, in this application, refers to breaking the compressed product into large particles.
Typical applications include pharmaceutical dosing; where the dose amount of a particular product has a low bulk density. Often the desired dosage can not fit within the ideal volume of a tablet or capsule. With compaction and granulation, the end product, a higher bulk density granule can fit within the ideal volume.
This technology can also be used in chemical applications to increase the bulk density so a products shipping weight/volume ratio can be increased or to change how a chemical product is distributed and dissolved, such as with dry powder laundry detergent.